Ancient schwannoma in oral cavity: a report of two cases
김나래, 정동해, 박대송, 김동우, 이상칠, 김성용, 임호용, 염학열, 김현민,
소속 상세정보
김나래 ( Kim Na-Rae ) - Gachon University Gil Hospital Department of Pathology
정동해 ( Chung Dong-Hae ) - Gachon University Gil Hospital Department of Pathology
박대송 ( Park Dae-Song ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
김동우 ( Kim Dong-Woo ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
이상칠 ( Lee Sang-Chil ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
김성용 ( Kim Sung-Yong ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
임호용 ( Lim Ho-Yong ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
염학열 ( Yeom Hak-Yeol ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
김현민 ( Kim Hyeon-Min ) - Gachon University Gil Hospital Department of Oral and Maxillofacial Surgery
KMID : 0355620110370060530
Abstract
This paper reports two cases of schwannomas arising from the oral cavity. One is an intraoral ancient schwannoma located at the left cheek, which evolved over a period of 13 years. The tumor was a well-demarcated buccal mass, which was located in the left lower first premolar area, with an obliterated the buccal vestibule, leaving the overlying mucosa intact. The second case was a central intraosseous schwannoma located from the left lower 1st molar periapical area to the left 3rd molar periapical area. Pathologically, the first mass was composed of the spindle shaped tumor cells with wavy nuclei beneath the fibroconnective tissue of the gingiva but second case mass was not. Occasional nuclear pleomorphism was observed but mitosis or necrosis was absent. There were Antoni A and B areas along with strong, diffuse staining with the S-100 protein. Ancient schwannomas were diagnosed. Schwannoma is a slow-growing benign tumor, and an ancient schwannoma that shows cellular atypism is a variant of a schwannoma caused by purely degenerative changes. To date, only limited cases of ancient schwannomas in the oral cavity have been reported.
키워드
Neurilemmoma;Mouth;S100 proteins
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